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Recharging the body’s cellular batteries


3 min read



In the world of anti-aging, Urolithin A has emerged as one of the most scientifically rigorous compounds for “recharging” the body’s cellular batteries. Unlike many supplements that rely on traditional lore, Urolithin A is backed by clinical trials showing it can physically improve muscle strength and cellular energy.

Urolithin A is a postbiotic — a compound produced by your gut bacteria after you eat certain fruits like pomegranates, strawberries, and walnuts.

Its “superpower” is a process called Mitophagy. Think of it as a “cellular spring cleaning.” As we age, our mitochondria (the energy-producing powerhouses in our cells) become damaged and cluttered.4 Urolithin A helps the body identify, recycle, and replace these “broken batteries” with fresh, efficient ones.

The “Gut Gap” Problem: Research shows that only about 30–40% of people have the specific gut bacteria required to convert food into Urolithin A. This is why direct supplementation has become the preferred route for longevity enthusiasts.

Key Benefits (Science-Backed)

  • Muscle Strength: A landmark study showed a 12% increase in muscle strength in middle-aged adults after months of use, even without changes in exercise.

  • Endurance: It has been shown to improve “VO2 max” (how well your body uses oxygen) and muscle endurance.

  • Immune Health: Recent 2024/2025 data suggests it helps “rejuvenate” blood stem cells, potentially strengthening the aging immune system.

Regulatory Status: FDA & FSSAI

One of the most common questions is whether Urolithin A is “approved.”

  • US FDA: The FDA does not “approve” dietary supplements the way it does prescription drugs. However, the leading brand of Urolithin A (Mitopure) has received GRAS (Generally Recognized As Safe) status from the FDA. This means the FDA has “no questions” regarding its safety for human consumption at recommended doses.

  • India (FSSAI): In India, Urolithin A is categorized as a nutraceutical. It is legal to sell and consume, provided the brand complies with FSSAI (Food Safety and Standards Authority of India) labeling and purity standards.

Brands and Availability in India

While Urolithin A is a premium supplement, it is increasingly accessible in India through international importers and local health-tech platforms.

Timeline (Mitopure) Mitopure Softgels/Powder. The “Gold Standard.” It is the specific brand used in most clinical human trials.

Codeage Liposomal Urolithin. Features a liposomal delivery system for potentially better absorption.

Neurogan Health Urolithin A 700mg Known for high-potency capsules (700mg vs the standard 500mg).

Local Importers Various (Biomall, etc.) Direct B2B/B2C Often available as raw powder or specialized capsules for the biohacking community.

Price Tip: Expect to pay between ₹8,000 to ₹15,000 for a month’s supply. Because the manufacturing process for pure Urolithin A is complex, “cheap” versions should be viewed with caution.

Patient Safety & Dosage

  • Dosage: Most clinical trials use 500mg to 1,000mg per day.15 500mg is typically sufficient for muscle health, while 1,000mg is often used for broader anti-inflammatory and immune benefits.

  • Side Effects: Human trials report no significant side effects.16 A small number of users report mild digestive upset.

  • Timing: It can be taken with or without food, though some users prefer taking it in the morning to align with their cellular energy cycle.

Important Disclaimer

Urolithin A is a supplement, not a replacement for medical treatment. If you are pregnant, nursing, or on chronic medication (especially for metabolic or heart conditions), consult your physician before starting.


 
 
 

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